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The landmark SUSTAIN-6 trial , published in The New England Journal of Medicine , found that Semaglutide significantly reduced the risk of major adverse cardiovascular events (such as heart attack, stroke, or death from cardiovascular causes) in patients with type 2 diabetes who were at high cardiovascular risk

It is recommended using the lowest possible effective dosage to get a satisfactory therapeutic response

The figure below shows real (adjusted for inflation) DSIP funds disbursed, with real expenditure and real revenue (excluding grants) since 1984

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