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Moreover, while the OUG defines an off-treatment period as at least 6 months, we defined it as 1 year, taking into account the rate of increase in BMI and other laboratory values after treatment discontinuation, as well as clinical expert opinion

The research is ongoing and largely based on non-human studies

The PlexusDx Precision Peptide Genetic Test identifies genetic variants in GLP-1 receptor pathways, FTO gene expression, and appetite-signaling molecules that influence both weight loss outcomes and potential side-effect susceptibility

Renal toxicity is typically detected as high serum creatinine levels, which usually prompt the discontinuation of ICIs