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Wang H, Chen X, Miao X, Lu K, He M, Wu X (2022) Dendrobium mixture improves gestational diabetes mellitus through regulating Nrf2/HO1 signaling pathway

The imbalance of G T and G D populations (or GTP and GDP) caused by the GEF activity-mediated exchange is restored by regulators of G protein-signaling (RGS) displaying GTPase activating protein (GAP) activity that converts G T back to G D via GTP hydrolysis

M.ArmengouA.CacabelosP.et al (2000)

It has been demonstrated that oxidative stress-mediated GSH depletion is crucial in controlling transient outward K+ currents in rat ventricular myocytes, which may be the cause of diabetes-related decreased contractility and aberrant electrical characteristics