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Folate, vitamin B12 and homocysteine status in the post-folic acid fortification era in different subgroups of the Brazilian population attended to at a public health care center

Most Common Side Effects Dry mouth Insomnia or disrupted sleep Increased heart rate or blood pressure Mild nausea (typically dose-related and temporary) Restlessness or mild anxiety in sensitive individuals Adverse events were mostly mild to moderate and occurred during early weeks of treatment

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Diet, supplements (e.g., niacin, NR), and exercise help, but may not suffice post-40 due to inefficiency and depletion.[18][19] Oral precursors like NMN increase NAD+ but bioavailability varies