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While intracellular Ca 2+ regulation and ion channel activity are proposed to be important in endometrial function, their precise roles remain largely unexplored, at least partly due to the lack of relevant in vitro models

"ATTAINMAINTAIN showed that orforglipron, a once-daily oral GLP-1, helped people maintain the weight they worked hard to lose." This data provides the first robust, Phase 3 evidence that an oral "step-down" or "switch" strategy is not just feasible but effective, offering a new pathway for the long-term management of obesity