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Lipid-induced insulin resistance in skeletal muscle: the chase for the culprit goes from total intramuscular fat to lipid intermediates, and finally to species of lipid intermediates

Your insulin sensitivity may also decline if you've regained fat tissue, making it harder to maintain a calorie deficit through diet and exercise alone

Citations Citations to this article as recorded by Comparative Analysis of Clinical Outcomes in Patients With Type 2 Diabetes Mellitus on Monotherapy Versus Combination Therapy Hariballav Mahapatra, Piyush Kumar Gupta, Ajo Paul, Amit Nampalliwar, Manju Bansal, Baijnath Das, K

also triggers mast cell histamine release as an off-target mechanism