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AN_001997) of Iranian descent was born to first-cousin parents

A decline in ACE2 function in aged individuals, coupled with the age-associated deterioration in mitochondrial functions results in chronic metabolic disorders like diabetes or cancer, and predisposes the host for increased susceptibility to infection, vulnerability to health complications, and intensifies the risk of mortality 163

The impact of KD on ROS and reactive nitrogen species (RNS) ROS are a group of chemically reactive molecules derived from molecular oxygen that arise primarily as byproducts of mitochondrial oxidative phosphorylation, although they can also be generated by enzymatic systems such as NADPH oxidases, xanthine oxidase, and cytochrome P450 enzymes [63]

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