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Pro-inflammatory cytokines disrupt neurotransmitter metabolism through mechanisms such as inhibited tryptophan conversion to serotonin while driving microglial activation, thereby amplifying neuroinflammation (271)

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et al (2020) The Role of Mitochondria in Cardiovascular Diseases Misrani, A et al (2021) Mitochondrial Dysfunction and Oxidative Stress in Alzheimers Disease Pinti, M

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Mechanistic synthesis: Melanotan-2 remains the reference tool for cross-referencing the four melanocortin receptors in comparative pharmacology

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