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This ecological remodeling of the oral-gut axis presents a plausible pathway through which dietary patterns influence brain function, supporting the emerging hypothesis that the Mediterranean diet exerts antidepressant effects via modulation of inflammatory and neuroendocrine pathways

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Cell Mol Life Sci 61(4):470487 Janok M, Kery V, Gaustadnes M, Maclean KN, Kraus JP (2001) Regulation of human cystathionine -synthase by S -Adenosyl-l-methionine: evidence for two catalytically active conformations involving an autoinhibitory domain in the C-terminal region