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37:71-82 e12 [PubMed: 25529979] 248

Does DPP-IV inhibition offer new avenues for therapeutic intervention in malignant disease

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The Results After 32 weeks of treatment: Biological age decreased by: 3.1 years (PCGrimAge) 4.9 years (PhenoAge) 2.3 years (GrimAge V2) Pace of aging slowed by 9% (DunedinPACE) Reductions were also seen in multi-omic and transposable-elementfocused clocks (OMICmAge and RetroAge) The strongest effects were seen in clocks associated with mortality risk, metabolic health, and systemic inflammation