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Fabiola De Marchi, Raffaele Dubbioso and Valentina Virginia Iuzzolino are members of the European Reference Network Euro-NMD

CagriSema appeared to have a safe and well-tolerated profile with most common adverse events being gastrointestinal, and the vast majority were mild to moderate and diminished over time

Discussion This review covers the importance of maintaining NAD + levels for cellular homeostasis and mitochondrial maintenance, as well as evaluating established and novel NAD + boosting strategies from simple supplementation of precursors to modulation of enzymes by drugs

Its versatility makes it relevant for both fitness-focused individuals and those seeking general physical support