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Ambiguously Related: A line of dialogue in "SpongeGuard on Duty" implies he was raised by a (now elderly) fish couple, though it is never elaborated on in any other episode

Conversely, ferroptosis-related release of oxidized byproducts and iron ions feeds back to escalate inflammation and further damage cartilage and synovium, establishing a vicious cycle

Moreover, exposure to IGF binding protein 5 (IGFBP5), the transport protein of IGF-1, provoked cellular senescence in human umbilical vein endothelial cells (HUVEC) [148] although the signaling pathway remained unknown