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Pregnant rats that underwent RUPP also exhibited immunological changes that are similar to MIA, including high levels of IL-6 and IL-17A that are produced by CD4 + T cells (236) and an increase in the number of Th17 cells (237)

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S100B protein levels have been incorporated into the Scandinavian Neurotrauma Committee guidelines (Undn et al., 2013), leading to a one-third reduction in the use of computed tomography among adults in the Scandinavian region and significantly lowering healthcare costs