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For instance, in metastatic melanoma, enrichment of JARID1B slow-cycling subpopulation was formed following the treatment with cisplatin and vemurafenib, inhibition of OXPHOS was then resulted in the suspension of JARID1B + subpopulation formation and making melanoma cells more vulnerable to chemotherapy agents [318] (Table 1)
doi: 10.3389/fendo.2026.1767726 Received 15 December 2025 Revised 26 March 2026 Accepted 30 March 2026 Published 30 April 2026 Volume 17 - 2026 Edited by Sadiq Umar, University of Illinois Chicago, United States Reviewed by Gustavo Roberto Cointry, National University of Rosario, Argentina Jiale Chen, Chengdu University of Traditional Chinese Medicine, China Updates Copyright 2026 Gong, Ma, Wang, Zhang, Liu, Li and Dong
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