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#7 Genetic Factors Genetic variations or mutations in genes associated with enzymes involved in glutathione synthesis can impact its production

14,15 Similarly, patients manifesting prodromal RBD demonstrate a higher prevalence of peripheral neurodegeneration, including severe constipation and enteric -synuclein deposition

The regulation of ferroptosis is multifaceted and involves numerous pathways and biomolecules involved in metabolism, iron regulation, and redox defenses (Figure 1)