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Among these targets, 71 were associated with A, Tau, A, and Tau (Figure 11A), specifically, PIK3CD, CDC42, PDE4D, HTR4, ADRA1B, ARG1, PTGS1, PRF1, ADRA2A, CD81, CRYAB, BACE1, CDK2, MDM2, ALDH2, CYP19A1, NOS2, CSNK1D, PRKACA, CSNK2A1, PLCG1, CBS, and MIF were significantly associated with A pathology, EPHB2, LCK, JUN, ZAP70, DPP4, HTR2B, MAPK10, HTR1A, VEGFA, HTR1B, CFTR, CHRM2, GBA2, GSTP1, MMP3, HTR3A, CD4, VDR, MAPK3, and CHEK2 were significantly associated with Tau pathology
Variants in GSS cause GSS protein deficiency or reduced GSS activity, resulting in lower GSH levels
Exp Gerontol 43:370377 Shen H, Oesterling E, Stromberg A, Toborek M, MacDonald R, Hennig B (2008) Zinc deficiency induces vascular pro-inflammatory parameters associated with NF-kappaB and PPAR signaling
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