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45 Conversely, the relative increase in heart rates secondary to GLP-1 RAs may be potentially beneficial in HFpEF due to the high prevalence of chronotropic incompetence in these patients

This review explores the therapeutic potential of GLP-1 RAs in AS, summarising pre-clinical and clinical data and elucidating the pathways through which GLP-1 RAs might offer renoprotective benefits

Distribution and localization of GPX1 in islet cells We observed inter-islet variability in the distribution and staining intensities of GPX1-positive islet cells in each donor and among different donors