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Abstract The STEP 5 trial assessed the efficacy and safety of once-weekly subcutaneous semaglutide 2.4 mg versus placebo (both plus behavioral intervention) for long-term treatment of adults with obesity, or overweight with at least one weight-related comorbidity, without diabetes

Our semaglutide weight-loss program has offered a compounded version of semaglutide combined with Vitamin B to reduce common side effects like fatigue and nausea

However, these changes reflect metabolic improvements associated with weight loss rather than any direct effect on the autoimmune process or thyroid gland itself