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The following additional adverse reactions have been reported rarely: vitiligo depigmentation, small depigmented spots, hypertrichosis, reddening (signs of keratosis pilaris), and exacerbation of recurrent herpes viral infection (i.e., herpes labialis)

The increased risk may relate to rapid weight loss, changes in gallbladder motility, or alterations in bile acid composition

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Salou, M., B