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The maximal emission was reached 36 h after injection of the nanoparticles (animal imaging: Fig
10.1124/jpet.109.160804 J
Similarly, in GPx1 / mice, deficiency of GPx1 increased ROS (as measured by DCF fluorescence of brain homogenates), lipid peroxidation, and protein carbonylation in brains exposed to the A peptide, whereas forced overexpression of GPx1 in the GPx1 / mice attenuated these detrimental effects [124]
Measurement of the TNF- and IL-1 by ELISA The TNF- and IL-1 levels in the perihematomal were determined using ELISA kits (USCN Life Science Inc., Wuhan, China) according to the manufacturers instructions
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