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Research shows that appetite suppression from GLP-1 agonists is dose-dependent and reversible

Furthermore, the GCGR may play a role in renal energy metabolism, and GLP-1R/GCGR dual agonists such as 1907B have shown superior efficacy to GLP-1R single agonists in murine DN models, more effectively reducing proteinuria and improving renal function [232]

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