By activating AMPK, MOTS-c essentially acts as a metabolic switch, guiding the cell towards a more energy-efficient and metabolically healthy state
It is produced in specialized cells called melanocytes, primarily found in the epidermisthe outer layer of our skin
[DOI] [PMC free article] [PubMed] [Google Scholar] 22.Gojkovic S., Krezic I., Vrdoljak B., Malekinusic D., Barisic I., Petrovic A., Horvat Pavlov K., Kolovrat M., Duzel A., Knezevic M., et al
(2) Microglia phagocytose myelin debris, which is important as myelin debris can inhibit OPC differentiation, while efficient clearance of myelin debris allows for effective remyelination after experimental demyelination in rodents (Kotter, 2006