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BMJ Open (2013) 3(9):e003201.10.1136/bmjopen-2013-003201 61 KahlesFMeyerCMllmannJDieboldSFindeisenHMLebherzCet alGLP-1 secretion is increased by inflammatory stimuli in an IL-6-dependent manner, leading to hyperinsulinemia and blood glucose lowering

Baseline data from American Society for Metabolic and Bariatric Surgery-designated Bariatric Surgery Centers of Excellence using the Bariatric Outcomes Longitudinal Database

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In Phase 2 trials, an average weight loss of up to approximately 20% in 52 weeks was reported in patients with obesity or overweight without type 2 diabetes, and up to approximately 17% in patients with type 2 diabetes