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In our previous study, the decrease in eGFR was slower in patients treated with SGLT2i than in those treated with GLP1Ra during monotherapy ( Another possible mechanism may be the difference in the mean BP at the time of drug treatment

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Therefore, while GLP-1RAs may represent a promising therapeutic option for managing psoriasis, further high-quality studies are needed to distinguish whether the therapeutic effects of GLP-1RAs originate from the direct regulation of immune cells or improvements in comorbidities such as obesity or diabetes

It can help prevent adverse effects from drugs and environmental toxins