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Insurance companies do not yet cover GLP-1s for being overweight (but not obese) nor for addiction

A mechanistic study showed that reductions in the function of the intestinal barrier promote the adhesion and colonization of Enterococcus , which triggers inflammatory signaling through cell wall-associated components, such as lipoteichoic acid (LTA), which are recognized by pattern recognition receptors, including TLRs, and subsequently activates NF-B-dependent inflammatory pathways 131

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To put that in perspective, a 32-gauge needle is significantly thinner than the needles used for standard blood draws or even most vaccinations