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In the context of addressing aspects of sarcopenia or age-related impairments in skeletal muscle, 21-22-month-old mice were administered either a regular chow diet or the same diet supplemented with sulforaphane for 12 week ( Bone Sulforaphane has also been proposed to protect against osteoclastic bone destruction in vitro ( via epigenetic mechanisms) and expression of the osteoclast activator receptor activator of nuclear factor-B ligand (RANKL) in osteocytes (Thaler et al., 2016)