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This prolonged gastric retention can increase intragastric pressure and potentially promote the reflux of stomach contents into the oesophagus, leading to symptoms of heartburn, regurgitation, and discomfort
All diets were based on the defined amino acid diet 5CC7
However, in most trials, participants received metformin, either as monotherapy or in combination with other agents, except for three trials where participants received no background glucose-lowering therapy after randomisation [26, 40, 49]
Regular monthly evaluations help track your progress, modifying dosage based on your tolerance and results
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