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However, the exact reason why Ozempic might cause depression in some users is not fully understood, and research on this topic is ongoing

All other GLP-1 medications, including Ozempic and Mounjaro, are currently FDA-indicated for people diagnosed with Type 2 diabetes

In addition, the transcription factor SRY-box transcription factor 2 (SOX2) has been shown to interact with Shh and regulate progenitor differentiation [67]

Glucagon also contributes to energy homeostasis by promoting satiety through vagal signaling to brainstem nuclei and by increasing resting energy expenditure through facultative thermogenesis in brown adipose tissue, skeletal muscle, and through promotion of WAT browning [22]