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Citrulline malate increases NO production and decreases muscle soreness

Children who benefit most from these medications are those who also receive guidance on nutrition, physical activity, sleep, and long-term behavior changes

Their primary hormonal action is on the somatotropic axis: more GH, more IGF-1, more protein synthesis, and more favorable partitioning between fat and lean mass

The compound's high membrane permeability and metabolic stability make it suitable for both acute and chronic study designs, but researchers should be aware that its effects on NAD+ and methylation metabolism may require time to fully manifest