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Some natural active ingredients (e.g., chitosan, hyaluronic acid) not only possess inherent anti-inflammatory and mucosal repair activities but can also serve as efficient delivery carriers to enhance the retention and bioavailability of 5-ASA at inflammatory sites, achieving dual functions of therapy and delivery ( 4 Discussion The combination of 5-ASA with TCM and its bioactive constituents represents an important advance in the therapeutic strategy for ulcerative colitis

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doi:10.1095/biolreprod.102.007500

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