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The glutathione can then be degraded by the cytoplasmic ChaC family of -glutamylamine cyclotransferases [ChaC1 (ChaC glutathione specific gamma-glutamylcyclotransferase 1) and ChaC2 (ChaC glutathione specific gamma-glutamylcyclotransferase 2)] generating 5-oxoproline and the dipeptide Cys-Gly

For patients with IBS-D (diarrhea-predominant), the slowed transit time might theoretically provide some symptomatic benefit by reducing bowel frequency and urgency, though clinical studies specifically examining this relationship in IBS populations are lacking

Because they bypass the digestive system, nutrients can be absorbed quickly for faster benefits

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