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The N-terminal tryptophan and three glycine residues give the molecule a flexible backbone that has not, in the published literature, been shown to adopt a stable secondary structure under physiological conditions

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When there is an overload of free radicals, natural Glutathione production gets depleted, losing its fighting power. Why we need to care about Depletion of Glutathione : When Glutathione is not plentifully available to battle against free radicals and fight off oxidative stress, the unstable molecules that produce oxidative stress are the beginning of chronic and degenerative diseases, lower energy, and even wrinkles