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Diabetes Drugs The same active ingredient can have very different FDA approvals, so the name on the box matters: Wegovy (semaglutide) FDA-approved for chronic weight management in adults with a BMI of 30 or higher, or 27 or higher with a weight-related condition (and for adolescents 12 and older with a BMI at or above the 95th percentile for their age and sex)

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