The CMA notes in a statement on its website that health insurance coverage "looks very different for weight management," with only a small number of private insurance plans offering "partial coverage." Meanwhile, says the CMA, "public drug plans generally do not cover them." T Since the original formulation can cost "several thousand dollars per year (when) insurance doesn't cover it, many Canadians have to pay out of pocket, making it hard to afford," said the CMA
For this reason, so-called incretin analogues have been developed in recent years, these are drugs that, like the intestinal hormone GLP-1, lead to the release of insulin in the pancreatic beta cells and at the same time reduce the feeling of hunger in the brain
These medications include insulin injections and sulfonylurea drugs, such as Glucotrol (glipizide), DiaBeta (glyburide), Amaryl (glimepiride), and others
The most frequently reported AEs are gastrointestinal in nature, including nausea, vomiting, diarrhea and constipation, reflective of the effects of GLP-1 agonists on the gastrointestinal system
