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Among the most promising markers there are: urinary melatonin metabolites (such as 6-sulfatoxymelatonin or aMT6s), salivary or serum cortisol profiles, DNA methylation signatures in clock and tumor suppressor genes, telomere elongation patterns, and altered circulating microRNAs (miRNAs) levels 32,33

GHK-Cus tissue-level changes build progressively over weeks and months

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