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Doctors often rely on symptoms, patient history, and clinical judgment, especially when tests are inconclusive

While this flexibility can increase access and lower costs, it introduces variability that could impact efficacy and patient safety

We extracted ten pre-specified variables: (1) comorbidity prevalence, (2) mean age, (3) gender ratio, (4) publication year, (5) EQ-5D version (3L/5L), (6) region (Europe, Americas, Asia, Oceania, Middle East), (7) sampling method, (8) administration mode, (9) survey venue, and (10) language

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