A study found that for patients with AIS combined with high heart rate at admission, for every 10 beats per minute increase in heart rate, the relative risk of in-hospital death increased by 40% (287)
Waziry R, Ryan CP, Corcoran DL, Huffman KM, Kobor MS, Kothari M, Graf GH, Kraus VB, Kraus WE, Lin DTS, Pieper CF (2023) Effect of long-term caloric restriction on DNA methylation measures of biological aging in healthy adults from the CALERIE trial
Knockdown of HSPA5 inhibits the migration and invasion of bladder cancer cells by inhibiting the vascular endothelial growth factor A (VEGFA)/vascular endothelial growth factor receptor 2 signaling pathway, and overexpression of VEGFA alleviates the effects of HSPA5 downregulation
Berberine can also cause mild nausea in some individuals