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demonstrated that although the combination therapy (metformin 1000 mg BID + liraglutide 1.2 mg/day) resulted in a greater weight loss than liraglutide alone, both groups showed an increase in SHBG and a decrease in free testosterone, with no differences between the two treatment arms, thus suggesting that the effect on the biochemical hyperandrogenism of liraglutide may be partially independent of the extent of weight loss [60]

Neurosci Lett 199:152154 Beal MF, Ferrante RJ, Browne SE et al (1997) Increased 3-nitrotyrosine in both sporadic and familial amyotrophic lateral sclerosis

[DOI] [PubMed] [Google Scholar] 259.Keefe MS, Benjamin CL, Casa DJ, et al