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SA forms an active monomeric form by regulating the depolymerization of NPR1

Excessive dosages can lead to receptor desensitization (making the peptides less effective over time) and an increased risk of side effects

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Glucocorticoids are widely prescribed for inflammatory and autoimmune diseases including multiple sclerosis, rheumatoid arthritis, ulcerative colitis, psoriasis and eczema[x] According to WADA, All glucocorticoids are prohibited when administered by oral, intravenous, intramuscular or rectal routes. Read how a cricketer was suspended due to inadvertently ingesting a glucocorticoid that is prohibited in competition