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These included GLP-1RA treatment for durations ranging from 10 to 104 weeks, with post-cessation follow-up periods ranging from 4 weeks to up to 2 years

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Many GLP-1s are FDA approved for more than just weight loss, including type 2 diabetes, cardiovascular risk reduction, and even stroke prevention in certain populations, says Supriya Rao, MD, an obesity physician and the director of medical weight loss at Lowell General Hospital in Lowell, Massachusetts

The tirzepatide dosage usually starts at a lower level to help the body adjust