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However, it is important to be aware of the following: Possible Side Effects : Some people may experience mild side effects, such as gastrointestinal upset, nausea, or diarrhea

Intracellular -KG can be further catalyzed to generate 2-hydroxyglutarate (2-HG) by isocitrate dehydrogenase (IDH1), a missense mutant metabolizing enzymes (19)

The copper-binding mechanism is central to GHK-Cu's anti-inflammatory effects