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However, research into GLP-1 receptor agonists' direct effects on sleep architecture remains limited

What Mechanistic Evidence Can and Cannot Prove Rodent mechanistic findings support why the warning exists Human mechanistic data does not confirm a comparable risk pathway Therefore, the burden shifts to high-quality human data Bottom Line: If GLP-1 drugs caused MTC in humans like in rodents, we'd expect clearer biologic signals in human C-cells and biomarkers

Nach einer soeben publizierten Studie sind sie aber auch bei einem T2DM mit einer CKD bezglich renaler und kardialer Endpunkte hoch effektiv

Cancer Cell 5 , 417421 (2004)