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Head Neck 2006

While medications that reduce alcohol intake such as naltrexone and acamprosate have central nervous system action, disulfiram reduces alcohol intake through peripheral mechanisms

In the following excerpt, Derek talks to David Ricks about the genesis and evolution of GLP-1 drugs

It was first reported by Sawyer, Hruby, Hadley and colleagues in the Proceedings of the National Academy of Sciences in 1980, and it departs from native human alpha-MSH at only two of thirteen positions: norleucine replaces the oxidation-prone methionine at position 4, and the phenylalanine at position 7 is inverted to its D-enantiomer