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Metabolites can regulate insulin sensitivity directly by modulating components of the insulin signalling pathway, such as insulin receptor substrates (IRSs) and AKT, and indirectly by altering the flux of substrates through multiple metabolic pathways, including lipogenesis, lipid oxidation, protein synthesis and degradation and hepatic gluconeogenesis

Biotransformation of Dioscorea nipponica by rat intestinal microflora and cardioprotective effects of diosgenin

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Sauting onions in healthy fats like olive oil or avocado oil helps your body absorb the fat-soluble nutrients found in the rest of your meal