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(PMC) Not well supported: That AOD-9604 produces durable, clinically meaningful fat loss in modern standards (especially compared with GLP-1s)

Jung, Y.-H., Kim, H., Kim, H., Kim, E., Baik, J., & Kang, H

GLP-1 Receptor Agonists Published April 1, 2026 N Engl J Med 2026;394:1313-1324 DOI: 10.1056/NEJMra2500106 Summary Glucagon-like peptide-1 (GLP-1) receptor agonists are incretin analogues that promote glucose-mediated insulin release and are used to treat type 2 diabetes mellitus and obesity

However, the researchers were unable to confirm whether AMY109 also reduced the pain that the condition causes, or whether it improved fertility