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doi: 10.1038/s41586-019-1707-0 46 BersukerKHendricksJMLiZMagtanongLFordBTangPHet al

During running or high-impact activity, that multiplier increases further

These findings suggest that research into the therapeutic modulation of FOXO4 activity, such as through the use of the synthetic peptide FOXO4-DRI, could provide insight into the heart's natural protective mechanisms and degenerative changes associated with aging

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