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Coffee has mild prokinetic effects and can stimulate colonic contractions
But these were different trials, different populations, and different primary endpoints
As documented in clinical literature, patients who do not respond incur burdensome personal financial costs for these treatments, are unnecessarily exposed to adverse effects, and draw significant healthcare resources with multiple healthcare visits
These findings highlight the importance of accounting for hormonal cycles in alcohol-memory research and future studies should incorporate estrous cycle monitoring to more accurately assess sex-specific vulnerability to alcohol-related memory impairment
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