This allows these damaged or dysfunctional cells to persist, which can contribute to tissue dysfunction, inflammation, and aging-related diseases
In a total of 20 studies (14 observational studies, 1 intervention study, and 5 rodent studies) for the systematic evaluation and analysis of VD and PD, it was reported in a meta-analysis of six observational studies reporting differences in VD levels that mean serum 25(OH)D levels in PD patients were lower than those in healthy controls, five studies in animal models of PD showed that supplemental VD intake in rodents significantly increased the concentrations of tyrosine hydroxylase, promoted the conversion of dopamine neurotransmitter, significantly decreased oxidative damage to the substantia nigra, and significantly increased dopamine levels and neuronal survival in the substantia nigra (87)
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SARS-CoV-2 infection modulates the community composition and diversity of nasopharyngeal microbiomes To shed light on the effects of SARS-CoV-2 infections in the diversity and composition of human nasal microbiome, we analyzed RNAseq data of nasopharyngeal samples of randomly selected healthy human, COVID-19 and recovered patients (Fig