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Quantification of Iba1 + cells was performed using ImageJ software, with results expressed as fluorescence intensity per mm 2 or mean fluorescence intensity (MFI)

These medications illustrate the core tension running through longevity medicine: they are prescription drugs with FDA approval for specific, well-established conditions, but their use in healthy-aging contexts represents off-label prescribing grounded in research interest rather than proven longevity outcomes in humans

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Lets go back to the original cases we discussed earlier to put this into perspective