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Furthermore, numerous effective small molecules targeting NRF2, an important transcription factor that regulates antioxidant genes, have been developed and show promising therapeutic effects in multiple diseases

The reality is more nuanced: The critical difference is clinical validation depth

Participants with OCD showed significantly higher levels of Glu (independent sample t -test(58) = 2.08, p = 0.02, p -FDR = 0.04, Cohens d = 0.53 , 95% CI[0.016, 0.83]), Glu:GABA ratio (MannWhitney U = 618, p = 0.006, p -FDR = 0.02, p 2 = 0.10, 95% CI[0.05, 0.70]), and Glx (independent sample t -test(58) = 2.13, p = 0.02, p -FDR = 0.05, Cohens d = 0.55 , 95% CI[0.03, 1.13]) within the ACC voxel

Open COA image Related compounds Same research category.